BioCyc genome database collection

BioCyc is a collection of 19534 [as of 2021] Pathway/Genome Databases (PGDBs), plus software tools for understanding their data. It allows users to visualize the layout of genes within a chromosome, or of an individual biochemical reaction, or of a complete biochemical pathway. BioCyc provides a reference on the genomes and metabolic pathways of thousands of sequenced organisms. BioCyc PGDBs are generated by software that predict the metabolic pathways of completely sequenced organisms, predict which genes code for missing enzymes in metabolic pathways, and predict operons. BioCyc also integrates information from other bioinformatics databases, such as protein feature and Gene Ontology information from UniProt. The BioCyc website provides a suite of software tools for database searching and visualization, for omics data analysis, and for comparative genomics and comparative pathway questions.
Access to BioCyc is being provided by the NC State University Libraries via a time-limited trial. Access will end on March 31, 2023. Renewal beyond that date will be subject to review.